Ilexhainanoside D ( —— )

产品货号. M31645 CAS No. 1137648-52-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ilexhainanoside D
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Ilexhainanoside D is a natural product from Periploca sepiumBge.
产品描述

Ilexhainanoside D is a natural product from Periploca sepiumBge.
体外实验

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体内实验

The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240?mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of Firmicutes/Bacteroidetes, reduces the relative abundance of Desulfovibrio and increases the relative abundance of Akkermansia. The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines.
同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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